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Get Advances in Structural Biology, Volume 6 (Advances in PDF

By S.K. Malhotra

ISBN-10: 0080526519

ISBN-13: 9780080526515

ISBN-10: 0762305940

ISBN-13: 9780762305940

According to the vast targets set for the serial ebook of Advances in Structural Biology, quantity 6 includes exhaustive articles from specialists in different components of biomedical study. the typical thread one of the quite a few articles is their relevance to the functions of telephone biology to human overall healthiness.

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Extra info for Advances in Structural Biology, Volume 6 (Advances in Structural Biology)

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D. PCI . . . . . . . . . . . . . . . . . . . . . . . . . . . . Summary and Conclusions . . . . . . . . . . . . . . . . . . . . . References . . . . . . . . . . . . . . . . . . . . . . . . . . . I. 56 56 57 58 59 59 60 BACKGROUND Glucose homeostasis is maintained in vivo through a balance between glucose disposal in multiple tissues, glucose production by hepatocytes, and absorption via the small intestine.

I. 56 56 57 58 59 59 60 BACKGROUND Glucose homeostasis is maintained in vivo through a balance between glucose disposal in multiple tissues, glucose production by hepatocytes, and absorption via the small intestine. In mammalian cells, glucose crosses cell membranes by facilitated diffusion mediated by a family of closely related glucose transport proteins (Gluts). Glucose transport into cells is essential for survival. , skeletal muscle, adipose, and cardiac) by binding its receptor on the cell surface and activating a series of reactions that leads ultimately to glucose uptake by a specific transporter, Glut4.

CGH requires no prior knowledge of the genomic region to be studied. However, CGH is not without limitations. Indeed, the following shortcomings of CGH have prevented its routine application in the average clinical cytogenetics laboratory. For example, CGH can spot sequence copy number changes only if greater than 50% of the cells analyzed contain a chromosome gain or loss. This means that the sequence copy changes in tumors which have many heterogeneous populations of normal and stromal cells may very likely evade detection.

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Advances in Structural Biology, Volume 6 (Advances in Structural Biology) by S.K. Malhotra


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